Background:

This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms.

Applications:

ELISA, WB, IHC

Name of antibody:

GSTZ1

Immunogen:

Fusion protein of human GSTZ1

Full name:

glutathione S-transferase zeta 1

Synonyms:

MAI; MAAI; MAAID; GSTZ1-1

SwissProt:

O43708

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human cervical cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

24 kDa

WB Positive control:

Mouse liver tissue and HepG2 cell lysates

WB Recommended dilution:

1000-5000